Table 1 Characteristics of study population

Total

7,338

467

6,871

Age (mean, sd)

69.9

(13.1)

73.8

(10.5)

69.7

(13.3)

Age categories, n(%)

 18–39

222

(3.0)

2

(0.4)

220

(3.2)

 40–64

1,826

(24.9)

81

(17.3)

1,745

(25.4)

 65–74

1,745

(23.8)

111

(23.8)

1,634

(23.8)

 75 -

3,545

(48.3)

273

(58.5)

3,272

(47.6)

Sex, n(%)

 Male

3,671

(50.0)

215

(46.0)

3,456

(50.3)

 Female

3,667

(50.0)

252

(54.0)

3,415

(49.7)

Observation period (median, interquartile range)

881

(885.8)

661.0

(921.5)

900.0

(887.0)

Comorbidities, n(%)

 Myocardial infarction

161

(2.2)

7

(1.5)

154

(2.2)

 Congestive heart failure

1,382

(18.8)

111

(23.8)

1,271

(18.5)

 Peripheral vascular disease

772

(10.5)

37

(7.9)

735

(10.7)

 Cerebrovascular disease

1,079

(14.7)

62

(13.3)

1,017

(14.8)

 Dementia

284

(3.9)

26

(5.6)

258

(3.8)

 Chronic pulmonary disease

1,280

(17.4)

94

(20.1)

1,186

(17.3)

 Rheumatic disease

296

(4.0)

18

(3.9)

278

(4.0)

 Peptic ulcer disease

1,491

(20.3)

145

(31.0)

1,346

(19.6)

 Mild liver disease

7,338

(100.0)

467

(100.0)

6,871

(100.0)

 Diabetes without chronic complication

512

(7.0)

46

(9.9)

466

(6.8)

 Diabetes with chronic complication

696

(9.5)

36

(7.7)

660

(9.6)

 Hemiplegia or paraplegia

71

(1.0)

1

(0.2)

70

(1.0)

 Renal disease

731

(10.0)

41

(8.8)

690

(10.0)

 Any malignancy

1,612

(22.0)

190

(40.7)

1,422

(20.7)

 Moderate or severe liver disease

492

(6.7)

254

(54.4)

238

(3.5)

 Metastatic solid tumor

118

(1.6)

7

(1.5)

111

(1.6)

 AIDS/HIV

18

(0.2)

1

(0.2)

17

(0.2)

Charlson comorbidity index (CCI) score (median, interquartile range)

3.0

(2.0)

5.0

(2.0)

3.0

(2.0)

Number of comedication (median, interquartile range)

9

(11.0)

14.0

(14.0)

9.0

(12.0)

Medical institution information: Number of the beds, n(%)

 unknown

29

(0.4)

0

(0)

29

(0.4)

 < 20

772

(10.5)

30

(6.4)

742

(10.8)

 20–99

200

(2.7)

8

(1.7)

192

(2.8)

 100–199

724

(9.9)

36

(7.7)

688

(10.0)

 200–299

586

(8.0)

27

(5.8)

559

(8.1)

 300–399

1,100

(15.0)

54

(11.6)

1,046

(15.2)

 400–500

784

(10.7)

51

(10.9)

733

(10.7)

 500 <=

3,143

(42.8)

261

(55.9)

2,882

(41.9)

Medical institution information: Hub hospital for cancer treatment, n(%)

 Hub hospital for cancer treatment

3,327

(45.3)

273

(58.5)

3,054

(44.4)

Type of HCV, n(%)

 Decompensated cirrhosis

149

(2.0)

129

(27.6)

20

(0.3)

 Compensated cirrhosis

234

(3.2)

10

(2.1)

224

(3.3)

 Chronic hepatitis C

5,963

(81.3)

247

(52.9)

5,716

(83.2)

 Others

992

(13.5)

81

(17.3)

911

(13.3)