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Table 2 Terms with strong co-occurrence relationships with “antimicrobials” (Dice coefficient ≥ 0.3)

From: Qualitative changes in clinical records after implementation of pharmacist-led antimicrobial stewardship program: a text mining analysis

 

Pre-ASP (n = 1,353)

Post-ASP (n = 5,155)

Term

Frequency a

Co-occurrence b

Frequency a

Co-occurrence b

ALT

  

1,677 (32.5)

0.491

AST

  

1,740 (33.8)

0.505

Administration

282 (20.8)

0.345

1,378 (26.7)

0.422

Bacterial Test

  

936 (18.2)

0.307

CRP

338 (25.0)

0.400

2,457 (47.7)

0.646

Caution

420 (31.0)

0.474

1,114 (21.6)

0.355

Ceftriaxone

  

975 (18.9)

0.318

Continuation

  

1,041 (20.2)

0.336

Creatinine

459 (33.9)

0.507

2,258 (43.8)

0.609

Decrease

  

1,056 (20.5)

0.340

Discontinuation

  

946 (18.4)

0.310

Dosage

296 (21.9)

0.359

  

Drugs

428 (31.6)

0.481

1,098 (21.3)

0.351

eGFR

366 (27.1)

0.426

2,179 (42.3)

0.594

Explanation

378 (27.9)

0.437

  

Fever

  

1,044 (20.3)

0.337

Guidance

364 (26.9)

0.424

  

Hospitalization

  

1,014 (19.7)

0.329

Initiation

358 (26.5)

0.419

1,270 (24.6)

0.395

Laboratory Test

482 (35.6)

0.525

2,609 (50.6)

0.672

Management Method

281 (20.8)

0.344

  

Med. Adherence

353 (26.1)

0.414

  

Med. Reconciliation

310 (22.9)

0.373

916 (17.8)

0.302

Med. Taking

276 (20.4)

0.339

931 (18.1)

0.306

Medicine

370 (27.3)

0.430

  

Modification

315 (23.3)

0.378

1,424 (27.6)

0.433

Necessity

618 (45.7)

0.627

1,025 (19.9)

0.332

Neutrophil

  

1,543 (29.9)

0.461

Oral Administration

327 (24.2)

0.389

1,344 (26.1)

0.414

Particularly

497 (36.7)

0.537

  

Prescription

384 (28.4)

0.442

1,258 (24.4)

0.392

Qualitative Test

  

1,497 (29.0)

0.450

Renal Function

346 (25.6)

0.407

  

Report

266 (19.7)

0.329

  

SBT/ABPC

  

1,062 (20.6)

0.342

Safety

434 (32.1)

0.486

  

Tablet

387 (28.6)

0.445

1,260 (24.4)

0.393

Take

333 (24.6)

0.395

979 (19.0)

0.319

Tend

  

1,158 (22.5)

0.367

Verification

698 (51.6)

0.681

2,124 (41.2)

0.584

WBC

  

2,113 (41.0)

0.582

  1. a Numbers in parentheses indicate the percentage of records containing the corresponding term
  2. b Dice coefficients indicate the strength of co-occurrence relationships
  3. Blank cells indicate that the term was not detected or did not meet the threshold for co-occurrence (Dice coefficient ≥ 0.3) in that period
  4. Abbreviations: ALT, alanine aminotransferase; ASP, antimicrobial stewardship program; AST, aspartate aminotransferase; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; Med., medication; SBT/ABPC, sulbactam/ampicillin; WBC, white blood cell count