Table 1 Summary of physicians’ approaches to promote the appropriate use of drugs using CDSSs when entering prescriptions
References | System features | Key results |
|---|---|---|
Chertow et al [23] | A system notified prescribers of the dosage and dosage intervals based on kidney function when entering a prescription for hospitalized patients | The rates of appropriate prescriptions according to kidney function during the intervention and control periods were 67% and 54% (p < 0.001) by dose and 59% and 35% (p < 0.001) by frequency, respectively |
Terrell et al. [24] | A system provided dosage recommendations for targeted medications for patients in an academic emergency department when the patient’s eCCr level was below the dosage adjustment threshold when physicians entered the prescription | Physicians in the intervention group were provided with 73 alerts, 31 (42%) of which did not result in a dose reduction appropriate for kidney function, whereas physicians in the control group were provided with 46 alerts, 34 (74%) of which did not result in a dose reduction appropriate for kidney function (p = 0.001) |
Awdishu et al. [25] | A system alerted prescribers to reduce dosage based on kidney function when they entered a prescription in ambulatory and acute settings | The rates of dose adjustment based on kidney function due to alerts at the time of prescription entry in the intervention and control groups were 55.6% (130/234) and 21.5% (52/242), respectively, and were significantly higher in the intervention group (p < 0.0001) |