Fig. 5

Fold changes in plasma (a) NPY, (b) leptin, (c) acyl-ghrelin, (d) motilin, and (e) substance P levels with respect to baseline (day 1, before administration of chemotherapy) in the anorexia (red circles and lines; n = 7) and non-anorexia (blue circles and lines; n = 10) groups. Data are expressed as mean (circle) ± standard deviation (vertical bar). Significant differences between groups were analyzed by Dunnett's test. **p < 0.01, ***p < 0.001, compared to day 1. NPY, neuropeptide Y