Table 1 Patient characteristics
Characteristics | Modeling dataset (n = 159) Number (%) or median (min–max) | Validation dataset (n = 133) Number (%) or median (min–max) |
|---|---|---|
Age (years) | 84 (75–99) | 81 (75–101) |
 75–84 | 80 (50.3) | 86 (64.7) |
 85–94 | 73 (45.9) | 46 (34.6) |
 ≥ 95 | 6 (3.8) | 1 (0.8) |
Sex (male/female) | 92 (57.9)/67 (42.1) | 69 (51.9)/64 (48.1) |
Height (cm) | 158 (135–180) | 157 (137–182) |
Body weight (kg) | 47 (26–70) | 49 (29–70) |
Body Mass Index (kg/m2) | 18.6 (11.0–24.8) | 20.0 (11.9–24.9) |
 < 18.5 | 77 (48.4) | 38 (28.6) |
Serum creatinine (mg/dL) | 0.64 (0.22–3.00) | 0.69 (0.24–5.68) |
 < 0.60 | 67 (42.1) | 40 (30.1) |
Estimated creatinine clearance (mL/min) | 51.5 (9.7–121.2) | 50.9 (7.7–110.6) |
 ≤ 50.0 | 75 (47.2) | 63 (47.4) |
The glomerular filtration rate estimated from creatinine (mL/min) | 65.5 (12.4–159.1) | 68.4 (7.5–195.4) |
 ≤ 50.0 | 45 (28.3) | 25 (18.8) |
Serum albumin (g/dL) | 2.3 (1.2–4.2) | 2.5 (1.2–4.4) |
 < 2.0 | 31 (19.5) | 19 (14.3) |
 2.0–2.9 | 113 (71.1) | 85 (63.9) |
 3.0–3.5 | 9 (5.7) | 19 (14.3) |
 ≥ 3.6 | 6 (3.8) | 10 (7.5) |
 Daily maintenance dose of Vancomycin (mg/day) | 1500 (250–3000) | 1500 (300–3000) |
 < 1000 | 44 (27.7) | 31 (23.3) |
 1000–2000 | 108 (67.9) | 98 (73.7) |
 > 2000 | 7 (4.4) | 4 (3.0) |