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Table 5 Percentage of nephrotoxicity based on AUCss (n = 212)

From: Vancomycin dosing design method considering risk factors for nephrotoxicity

AUCss

(mg·h/mL)

Low Risk groups

(n = 108)

High Risk groups

(n = 104)

All cases

(n = 212)

400

2.1%

16.8%

8.2%

500

4.7%

23.3%

13.4%

575

8.4%

29.3%

18.9%

600

10.2%

31.4%

21.1%

650

14.6%

36.0%

26.0%

  1. AUC: area under the concentration-time curve