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Table 4 Details of patients with discrepancies in medication continuity

From: Survey of medication history of patients with stroke after discharge from an acute hospital ward: a case series study

Patient No

Diagnosis for hospitalization

Categories

Medicinal efficacy classification

Definitiona

Details

Extra Information

1

Cerebral infarction

Addition of drugs

Other agents relating to blood and body fluids (antiplatelet drugs)

1

Aspirin was added to cilostazol

・Be prescribed single antiplatelet drug for having cerebral microbleeds

Dosage (same drugs)

Vasodilators

4

The dose of amlodipine was increased from 2.5 mg to 5 mg

 

Dosage (same drugs)

Agents for peptic ulcer

4

The dose of lansoprazole was increased from 15 to 30 mg

・Prescribing PPI to prevent aspirin-induced peptic ulcers

2

Cerebral infarction

Drug discontinuation

Antihypertensives

4

Doxazosin 1 mg, which was added during hospitalization, was discontinued

 

3

Cerebral infarction

Dosage (same drugs)

Agents for hyperlipidemia (HMG-CoA reductase inhibitors (statins))

1

The dose of pitavastatin was reduced from 2 to 1 mg pitavastatin

 

4

Cerebral infarction

Drug discontinuation

Other agents relating to blood and body fluids (antiplatelet drugs)

1

Clopidogrel was not prescribed. The community pharmacist made prescription inquiry to the physicians the cases but non approved by the physicians

 

Drug discontinuation

Agents for hyperlipidemia (HMG-CoA reductase inhibitors (statins))

1

Rosuvastatin was not prescribed

 

Dosage (same drugs)

Agents for peptic ulcer

4

The dose of rabeprazole has been reduced from 20 to 10 mg

・Considering the symptoms that suggest a recurrence of peptic ulcer, the PPI dose was increased

5

Transient ischemic attack

Addition of drugs

Other agents affecting digestive organs (antiemetic agent that acts on the central nervous system)

3

Discontinued metoclopramide has been resumed

 

6

Cerebral infarction

Dosage (same drugs)

Other agents relating to blood and body fluids (antiplatelet drugs)

1

The dose of clopidogrel has been reduced from 75 to 50 mg (the remaining drug was taken as prescribed before admission)

 

Addition of drugs

Vasodilators

4

2.5 mg of amlodipine was added

・She Visited her home doctor on the day of discharge

7

Cerebral infarction

Drug discontinuation

Other agents relating to blood and body fluids (antiplatelet drugs)

1

Aspirin was not prescribed. The community pharmacist made prescription inquiry to the physicians the cases but non approved by the physicians

・Taking 14 medications before admission and this number increased owing to recurrent stroke

・The interrupted Aspirin was resumed at the second follow-up visit

Dosage (same drugs)

Agents for hyperlipidemia (HMG-CoA reductase inhibitors (statins))

1

Pravastatin has been reduced from 15 to 5 mg. The community pharmacist made prescription inquiry to the physicians the cases but non approved by the physicians

  1. HMG-CoA 3-hydroxy-3-methylglutaryl-CoA lyase, PPI Proton-pump inhibitor
  2. aDefinition of discrepancy:
  3. 1. Medication recommended in the medical information prepared by the physicians specializing in stroke is discontinued (potentially increasing the risk of stroke recurrence)
  4. 2. A drug discontinued because it was suspected to cause side effects during hospitalization has been re-prescribed
  5. 3. A drug discontinued because the risk of side effects exceeded the benefits during hospitalization has been re-prescribed
  6. 4. The reason (evidence) for adding, changing or discontinuing a drug is unknown