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Table 4 Clinical outcomes and antibiotic use before and after the intervention in the matched cohorts

From: Impact of hospital formulary intervention on carbapenem use: a segmented time-series analysis of consumption and a propensity score-matched non-inferiority study of treatment efficacy

 

Before

After

n = 97

n = 97

Outcome = effective, n (%)

77

(79.4)

84

(86.6)

 Excellent

12

(12.4)

13

(13.4)

 Effective

65

(67.0)

71

(73.2)

Treatment duration(days), mean (SD)

11.07

(7.43)

10.51

(4.88)

Switching Antibiotics = TRUE, n (%)

31

(32.0)

14

(14.4)

Adverse effect = TRUE, n (%)

5

(5.2)

3

(3.1)

Antibiotics, n (%)

 Anti-MRSA

6

(6.2)

3

(3.1)

 Cephalosporine (2nd)

8

(8.2)

8

(8.2)

 Cephalosporine (3rd /4th)

3

(3.1)

1

(1.0)

 Carbapenem

32

(33.0)

11

(12.4)

  MEPM

24

(24.7)

9

(9.3)

  DRPM

7

(7.2)

1

(1.0)

  IPM/CS

1

(1.0)

1

(1.0)

 βl-Penicillin

77

(79.4)

47

(48.5)

  SBT/ABPC

29

(29.9)

10

(10.3)

  TAZ/PIPC

48

(49.5)

37

(38.1)

 βl-Cephalosporine

11

(11.3)

46

(47.4)

  SBT/CPZ

11

(11.3)

46

(47.4)

Others

4

(4.1)

1

(1.0)

  1. MRSA, methicillin-resistant Staphylococcus aureus; cephalosporine (2nd), second-generation cephalosporines; cephalosporine(3rd /4th), third-generation and fourth-generation cephalosporins; βl-Penicillin, penicillins combined with β-lactamase inhibitors; βl-Cephalosporin, cephalosporin combined with β-lactamase inhibitor