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Table 2 Identifying predictors of ARC by multivariate analysis

From: Development and validation of the prediction score for augmented renal clearance in critically Ill Japanese adults

 

Multivariate analysis

Score points

OR (95% CI)

Beta

p-value

Age

  < 36 years

96.3 (16.2–570)

4.6

 < 0.01

  7

 36–59 years

17.6 (6.02–51.2)

2.9

 < 0.01

  5

 60–79 years

8.35 (3.07–22.7)

2.1

 < 0.01

  3

 ≥ 80 years

Reference

–

–

  –

Male sex

1.87 (1.04–3.64)

0.63

 < 0.05

  1

SCr

 < 0.96 mg/dL

21.2 (6.00–74.9)

3.1

 < 0.01

  5

 0.96–1.19 mg/dL

9.82 (2.67–36.1)

2.3

 < 0.01

  4

 1.20–1.64 mg/dL

3.69 (0.94–14.5)

1.3

0.06

  –

 ≥ 1.65 mg/dL

Reference

–

–

  –

Admission diagnosis

 Trauma

2.49 (1.12–5.55)

0.9

 < 0.05

  1

 CNSa

3.18 (1.43–7.07)

1.2

 < 0.01

  2

 Sepsis

1.20 (0.40–3.58)

0.2

0.74

  –

 Cardiovascular

0.77 (0.41–1.47)

-0.3

0.43

  –

Medical historyb

0.58 (0.33–1.01)

-0.6

0.06

  –

  1. ARC augmented renal clearance, SCr serum creatinine, CNS central nervous system, OR odds ratio, 95% CI 95% confidence interval
  2. aCNS refers to hospitalization for any of the following reasons: traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, cerebral arteriovenous malformation, hydrocephalus, or status epilepticus
  3. bMedical history of chronic kidney disease, hypertension, diabetes, myocardial infarction, heart failure, chronic obstructive pulmonary disease, cirrhosis, and liver failure