In-vivo evaluation of analgesic and anti-inflammatory activities of the 80% methanol extract of Acacia seyal stem bark in rodent models

Table 3 Anti-Inflammatory activity of 80% A.seyal on cotton pellet caused granuloma in rodents

Group	Exudate (Mean ± SEM)	% reduction of Exudation
DW10	139.17 ± 4.14		38.91 ± 2.96
IND10	92.74 ± 2.11^a2b²d¹	33.4%	14.37 ± 1.06a²b²c¹	62.3%
ASME100	125.49 ± 2.77	9.85%	32.73 ± 2.42	15.9%
ASME200	112.448 ± 2.30a²	19.21%	26.35 ± 1.85a²b¹	32.3%
ASME400	104.51 ± 2.35a²b²	25%	20.59 ± 1.50a²b¹	47.1%

Notes Each value represents mean ± S.E.M; n = 6 for each treatment; Analysis was performed by one way ANOVA; a, compared to negative control group; b, compared to ASME100; c, compared to ASME200;¹P<0.05;²P<0.001. Numbers followed by IND and ASME indicate dose in mg/kg
Abbreviation; IND, indomethacin; DW, distilled water; ASME, Acacia seyal methanolic extract

ISSN: 2055-0294