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Fig. 2 | Journal of Pharmaceutical Health Care and Sciences

Fig. 2

From: Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis

Fig. 2

Violin plot of differences in corrected calcium level in patients with and without hypocalcaemia

Abbreviations: Ca; serum calcium X-axis and Y-axis represent categories and ΔCa levels, respectively. Solid and dotted lines are median and interquartile range. A difference in serum calcium level (ΔCa, mg/dL) between baseline and nadir was estimated by the equation. \(\triangle\mathrm{Ca}=\mathrm{serum}\;\mathrm{calcium}\;\mathrm{at}\;\mathrm{nadir}-\mathrm{serum}\;\mathrm{calcium}\;\mathrm{at}\;\mathrm{baseline}\) . Hypocalcaemia was defined as a serum calcium level < 8.5 mg/dL [12]. Serum calcium level was corrected when serum albumin level < 4.0 g/dL [13]. \(\text{Corrected calcium}=\text{serum calcium}+\left(4.0-\text{serum albumin}\right)\)

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