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Table 1 Baseline characteristics of the study patients

From: Evaluation of the drug-drug interactions management system for appropriate use of nirmatrelvir/ritonavir: a retrospective observational study

Categorya

Total (n = 241)

Age (years)

60 [45.0–73.0]

Female

112 (46.5%)

eGFR (mL/min/1.73 m2)

70.0 [50.9–85.1]

 Unknown

9

Number of severity risk factors

3 [2–5]

 ≥ 65 years of age

104 (43.2%)

 Malignancy

98 (40.7%)

 Chronic respiratory disease

28 (11.6%)

 Chronic kidney disease

80 (33.2%)

 Diabetes mellitus

53 (22.0%)

 Hypertension

104 (43.2%)

 Hyperlipidemia

71 (29.5%)

 Cardiovascular disease

53 (22.0%)

 Cerebrovascular disease

15 (6.2%)

 Body mass index ≥ 30 kg/m2

15 (6.2%)

 Smoking habit (within the past 30 days and more than 100 cigarettes in a lifetime)

20 (8.3%)

 Prior solid-organ transplant

17 (7.1%)

 Late pregnancy

3 (1.2%)

 Use of immunosuppressants (including cancer chemotherapy)

104 (43.2%)

 HIV infection (CD4 < 200 cells/mm3)

1 (0.4%)

Hospitalized patients

44 (18.3%)

Vaccination status

 0–1

44 (18.3%)

 ≥ 2

170 (70.5%)

 Unknown

27 (11.2%)

Prescribed COVID-19 medication

 NMV-r

126 (52.3%)

 MOV

115 (47.7%)

  1. COVID-19 the coronavirus disease 2019, eGFR estimated glomerular filtration rate, HIV human immunodeficiency virus, MOV molnupiravir, NMV-r nirmatrelvir/ritonavir
  2. aMedian [min–max] or n (%)