Table 1 Clinical characteristics after propensity score-matching
Variables | ESA alone, n=8 | ESA+TMP, n=8 | P value |
|---|---|---|---|
Demographical data | |||
Male, n (%) | 5 (63) | 3 (38) | 0.32 |
Age, years | 78 [70 to 86] | 72 [64 to 75] | 0.11 |
Body weight, kg | 64 [55 to 76] | 56 [51 to 78] | 0.24 |
Body mass index, kg/m2 | 23 [19 to 27] | 23 [20 to 26] | 0.75 |
Co-existing disease | |||
Hypertension, n (%) | 8 (100) | 8 (100) | - |
Heart failure, n (%) | 4 (50) | 2 (25) | 0.30 |
Diabetes, n (%) | 1 (13) | 3 (38) | 0.25 |
Clinical laboratory data | |||
Serum potassium, meq/L | 4.4 [4.2 to 4.7] | 4.2 [4.0 to 5.1] | 0.29 |
Serum sodium, meq/L | 140 [139 to 143] | 141 [139 to 143] | 0.46 |
Serum chloride, meq/L | 106 [104 to 108] | 109 [104 to 110] | 0.43 |
Serum albumin, g/dL | 3.7 [3.0 to 3.9] | 3.4 [2.9 to 3.7] | 0.56 |
Blood urea nitrogen, mg/dL | 25.1 [21.0 to 30.5] | 21.2 [17.4 to 26.6] | 0.25 |
Serum creatinine, mg/dL | 1.29 [1.00 to 1.82] | 1.00 [0.74 to 1.31] | 0.12 |
eGFR, mL/min/1.73m2 | 38.9 [27.8 to 45.4] | 50.9 [38.8 to 63.3] | 0.09 |
ESA | |||
0.625 mg ×1, n (%) | 0 (0) | 1 (13) | 0.30 |
1.25 mg ×1, n (%) | 7 (88) | 5 (63) | 0.25 |
2.5 mg ×1, n (%) | 1 (13) | 2 (25) | 0.52 |
3.75 mg ×1, n (%) | 0 (0) | 0 (0) | - |
5.0 mg ×1, n (%) | 0 (0) | 0 (0) | - |
TMP | - | ||
Daily administration, n (%) | - | 1 (13) | |
Non-daily administration, n (%) | - | 7 (88) | |
Medications | |||
ARNI or RASi, n (%) | 8 (100) | 6 (75) | 0.13 |
Loop diuretics, n (%) | 2 (25) | 2 (25) | 1.00 |
Thiazide diuretics, n (%) | 1 (13) | 1 (13) | 1.00 |
SGLT2i, n (%) | 0 (0) | 0 (0) | - |