Table 2 Comparison of study participants with and without acute kidney injury (AKI)

Sex, Male

6 (67%)

19 (73%)

0.694

Age (years)

76 (69, 78)

69 (57, 75)

0.190

Weight (kg)

49.6 (49.2, 59.1)

53.4 (46.6, 56.9)

0.610

BMI (kg/m²)

19.9 (19.5, 21.5)

20.1 (18.1, 24.1)

0.664

Treatment of gentamicin

Once daily dosing

8 (89%)

14 (54%)

0.109

Multiple daily dosing

1 (11%)

12 (46%)

-

Initial daily dosage (mg/kg)

2.50 (2.40, 3.00)

2.98 (2.30, 4.29)

0.180

Duration of administration (days)

13 (6, 15)

13 (10, 15)

0.648

Days to initial trough measurement

(days)

4 (4, 6)

4 (3, 5)

0.097

Renal function

Baseline serum creatinine (mg/dL)

0.63 (0.58, 0.94)

0.76 (0.55, 0.90)

0.956

Baseline eGFR (mL/min/1.73m²)

78.0 (61.0, 85.0)

77.5 (67.0, 107.3)

0.521

Drugs at risk for renal impairment

7 (78%)

18 (69%)

1.000

Loop diuretics

5 (56%)

9 (35%)

0.432

NSAIDs

2 (22%)

10 (38%)

0.450