Table 3 Comparison of analyte content in samples, determined by two methods
|  | Sample name | Spiked concentration (μg/mL) | RMS method (Calibrant: Carbamazepine) | RMS method (Calibrant: Caffeine) | Conventional method | |||
|---|---|---|---|---|---|---|---|---|
Concentration (μg/mL) | RSD (%) | Concentration (μg/mL) | RSD (%) | Concentration (μg/mL) | RSD (%) | |||
Carbamazepine spiked | Sample 1 | 20 | 21.1 | 1.9 | 21.1 | 1.9 | 21.1 | 1.9 |
Phenytoin spiked | Sample 2 | 2 | 2.1 | 0.9 | 2.1 | 0.9 | 2.1 | 0.9 |
Sample 3 | 20 | 18.0 | 2.5 | 18.1 | 2.5 | 18.1 | 2.5 | |
Voriconazole spiked | Sample 4 | 1 | 1.1 | 1.0 | 1.0 | 1.1 | 1.1 | 1.0 |
Sample 5 | 5 | 5.1 | 2.0 | 5.2 | 1.9 | 5.2 | 1.9 | |
Meropenem spiked | Sample 6 | 0.5 | 0.4 | 1.4 | 0.4 | 1.4 | 0.4 | 1.4 |
Sample 7 | 100 | 85.5 | 2.8 | 85.9 | 2.8 | 85.5 | 2.8 | |
Mycophenolic acid spiked | Sample 8 | 1 | 1.1 | 0.5 | 1.1 | 0.5 | 1.1 | 0.5 |
Sample 9 | 20 | 17.5 | 1.3 | 17.5 | 1.3 | 17.5 | 1.3 | |
Linezolid spiked | Sample 10 | 2 | 2.3 | 0.7 | 2.3 | 0.7 | 2.3 | 0.7 |
Sample 11 | 50 | 54.9 | 5.5 | 54.8 | 5.5 | 54.7 | 5.5 | |