Factors associated with incomplete adherence to integrase strand transfer inhibitor-containing single-tablet regimen among Japanese people living with HIV

Table 1 Demographic and clinical characteristics^a

Characteristics
Number of patients	387
Age (years), median (IQR)	47.0 (39.0–54.0)
Sex, n (%)
Male	370 (95.6)
Female	17 (4.4)
Education level^b, n (%)
Primary school/Secondary school	146 (37.7)
Vocational school/College of Technology/University	239 (61.8)
Missing data	2 (0.5)
Employment status^b, n (%)
Employed	308 (79.6)
Unemployed	63 (16.3)
Missing data	16 (4.1)
CD4 cell count (cells/µL), median (IQR)	570 (434–752)
HIV-RNA < 50 copies/mL, n (%)
Yes	377 (97.4)
No	10 (2.6)
Prior AIDS diagnosis^b, n (%)
Yes	124 (32.0)
No	262 (67.7)
Missing data	1 (0.3)
Time on ART (years), n (%)
< 5	121 (31.3)
5–9	122 (31.5)
≥ 10	144 (37.2)
INSTIs in the current regimen^c, n (%)
Bictegravir	203 (52.5)
Dolutegravir	162 (41.9)
Elvitegravir	22 (5.7)
Food requirements for the regimen, n (%)
Yes	30 (7.8)
No	357 (92.2)
Number of concomitant medications, n (%)
None	187 (48.3)
1–4	143 (37.0)
≥ 5	57 (14.7)
Total score of HIVTSQs^b, median (IQR)	59 (53–65)
Depression level^d, n (%)
Minimal	197 (50.9)
Mild	127 (32.8)
Moderate	36 (9.3)
Moderately severe	20 (5.2)
Severe	7 (1.8)

Abbreviations: AIDS Acquired immunodeficiency syndrome, ART Antiretroviral therapy, INSTI Integrase strand transfer inhibitor, HIVTSQs HIV treatment satisfaction questionnaire: status, PHQ-9 Patient health questionnaire-9
^aData are expressed as number (%) or median (IQR)
^bMissing data/nonresponses were excluded for the following variables: educational level (n = 2), employment status (n = 16), prior AIDS diagnosis (n = 1), and total score of HIVTSQs (n = 6)
^cThe sum may not equal 100% due to rounding to the second decimal place for each item in the table
^dThe total scores on the PHQ-9 were classified according to levels of depression severity as follows: 0–4 (minimal), 5–9 (mild), 10–14 (moderate), 15–19 (moderately severe), and 20–27 (severe)

ISSN: 2055-0294