Table 1 Characteristics of the patients at baseline
Main feature | Sub-feature | Number of patients | Â | ||
|---|---|---|---|---|---|
Total (n=30) | Melatonin (n=15) | Placebo (n=15) | P value | ||
Gender | Male | 9 (30) | 6 (40) | 3 (20) | 0.232 |
Female | 21(70) | 9 (60) | 12 (80) | ||
Age - no (%) (Mean± SD) | <50 y.o | 3 (10) | 2 (13.3) | 1 (6.6) | 0.383 |
≥50 y.o | 27 (90) | 13 (86.6) | 14 (93.3) | ||
BMI- no (%) | <30 | 9 (30) | 6 (40) | 3 (20) | 0.519 |
30-40 | 15 (50) | 7 (46.6) | 8 (53.3) | ||
≥40 | 6 (20) | 2 (13.3) | 4 (26.6) | ||
Education- no (%) | Illiterate | 1 (3.3) | 0 | 1 (6.6) | 0.558 |
<Diploma | 14 (46.6) | 7 (46.6) | 7 (46.6) | ||
Diploma | 10 (33.3) | 5 (33.3) | 5 (33.3) | ||
Bachelor | 4 (13.3) | 3 (20) | 1 (6.6) | ||
Dr | 1 (3.3) | 0 | 1 (6.6) | ||
Marital status- no (%) | Single | 2 (6.6) | 1(20) | 1(20) | 1.000 |
Married | 28 (93.3) | 14 (80) | 14 (80) | ||
Past medical history- no (%) | Non | 7 (23.3) | 4 (26.6) | 3 (20) | 0.545 |
1-2 diseases | 19 (63.3) | 10 (66.6) | 9 (60) | ||
≥ 3 diseases | 4 (13.3) | 1 (6.66) | 3 (20) | ||
PAP usage duration- no (%) | 1-6 months | 13 (43.3) | 3 (20) | 10 (66.6) | 0.068 |
7-12 months | 2 (6.6) | 2 (13.3) | 0 | ||
13-24 months | 4 (13.3) | 2 (13.3) | 2 (13.3) | ||
>24 months | 11 (36.6) | 8 (53.3) | 3 (20) | ||
Hypnotic usage history- no (%) | Non | 26 (86.6) | 13 (86.6) | 13 (86.6) | |
BDZ | 3 (10) | 1 (6.6) | 2 (13.3) | 0.513 | |
Trazodone | 1 (3.3) | 1 (6.6) | 0 | ||
Device type- no (%) | CPAP | 20 (66.6) | 10 (66.6) | 10 (66.6) | 0.721 |
Auto-PAP | 4 (13.3) | 2 (13.3) | 2 (13.3) | ||
BiPAP | 6 ( 3.3) | 3 (20) | 3 (20) | ||
Primary AHI- no. (%) | 15-30 events/hr. | 8 (26.6) | 5 (33.3) | 3 (20) | 0.463 |
>30 events/hr. | 22 (73.3) | 10 (66.6) | 12 (80) | ||