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Table 3 Qualitative histological analysis of skin wound healing for diabetic untreated rats (negative controls) and after treatment with Dermazin cream (positive controls), eggshell membrane (ESM), Ulva lactuca, and ESM + Ulva lactuca mixture powders of all study groups at day 21

From: Eggshell membrane and green seaweed (Ulva lactuca) micronized powders for in vivo diabetic wound healing in albino rats: a comparative study

 

Negative Controls

Dermazin Cream

Eggshell Membrane

Ulva lactuca

Mixture

Re-epithelization

++

+++

++++

++

++

Pigments

+

+++

+++

+

++

Keratinocytes

+

++

+++

+

++

Well basement membrane

++

+++

++++

+

+++

Infiltrating lymphocytes

+++

++

+

++

++

Organized collagen fibrines

+

++

++++

+

++

Congested blood vessels

++

+

+

++

++