Skip to main content

Table 1 Proportion of HBV screening performed for each drugs

From: A cross-sectional survey of hepatitis B virus screening in patients who received immunosuppressive therapy for rheumatoid arthritis in Japan

 

Total, n

Therapeutic Category (Alla), %)

All

HBsAg

HBsAb

HBcAb

csDMARDs

70,865

     

 Methotrexate

36,581

MTX (10.6)

3,893 (10.6)

1,121 (30.6)

4,736 (12.9)

5,252 (14.4)

 Salazosulfapyridine

15,555

Other csDMARDs (9.2)

1,818 (11.7)

5,537 (35.6)

2,201 (14.1)

2,489 (16.0)

 Leflunomide

187

5 (2.7)

37 (19.8)

9 (4.8)

8 (4.3)

 Tacrolimus

7,731

612 (7.9)

2,111 (27.3)

760 (9.8)

792 (10.2)

 Sodium aurothiomalate

98

3 (3.1)

8 (8.2)

3 (3.1)

3 (3.1)

 Bucillamine

5,957

277 (4.6)

1,733 (29.1)

373 (6.3)

423 (7.1)

 Iguratimod

4,542

419 (9.2)

1,698 (37.4)

516 (11.4)

623 (13.7)

 Mizoribine

214

9 (4.2)

51 (23.8)

11 (5.1)

10 (4.7)

bDMARDs

10,322

     

 Abatacept

1,802

CTLA4-Ig (6.3)

114 (6.3)

321 (17.8)

147 (8.2)

177 (9.8)

 Etanercept

1,961

TNF-α inhibitor (6.7)

109 (5.6)

348 (17.8)

135 (6.9)

148 (7.6)

 Infliximab

670

28 (4.2)

70 (10.5)

38 (5.7)

36 (5.4)

 Adalimumab

875

95 (10.9)

180 (20.6)

116 (13.3)

119 (13.6)

 Certolizumab pegol

358

23 (6.4)

68 (19.0)

34 (9.5)

40 (11.2)

 Golimumab

1,056

65 (6.2)

187 (17.7)

87 (8.2)

105 (9.9)

 Tocilizumab

3,418

Anti-IL-6R therapy (10.3)

334 (9.8)

723 (21.2)

381 (11.2)

410 (12.0)

 Sarilumab

182

35 (19.2)

66 (36.3)

37 (20.3)

41 (22.5)

tsDMARDs

1,095

     

 Tofacitinib citrate

543

Jak inhibitor (11.0)

36 (6.6)

102 (18.8)

40 (7.4)

49 (9.0)

 Baricitinib

463

73 (15.8)

215 (46.4)

80 (17.3)

85 (18.4)

 Upadacitinib hydrate

38

4 (10.5)

16 (42.1)

5 (13.2)

5 (13.2)

 Filgotinib maleate

10

1 (10.0)

4 (40.0)

2 (20.0)

2 (20.0)

 Peficitinib hydrobromide

41

6 (14.6)

13 (31.7)

6 (14.6)

7 (17.1)

  1. HBV Hepatitis B virus, HBsAg Hepatitis B surface antigen, HBsAb Hepatitis B surface antibody, HBcAb hepatitis B core antibody, DMARDs Disease-modifying antirheumatic drugs, csDMARDs Conventional synthetic DMARDs, bDMARDs Biological DMARDs, tsDMARDs Targeted synthetic DMARDs, MTX methotrexate, CTLA4-Ig Cytotoxic T-lymphocyte antigen 4-immunoglobulin, TNF Tumour necrosis factor, IL-6R Interleukin-6 receptor. a) All; HBV screening (HBsAg, HBsAb, and HBcAb) was performed