Fig. 3

In vitro penetration profile (A) and AUC_penetration (B) of FEL-MP and FEL-NP gels. A Franz diffusion cell with rat skin was used. n = 8. ^* P < 0.05, vs. FEL-MP gel for each category. The penetration of FEL-NP gel was significantly increased compared with FEL-MP gel