Fig. 3

Neuronal death assessed by PI staining is rescued by NYT diet. PI fluorescence was measured in the granule cell layer (GCL) of mice surrounded by the dotted line 14 days after ICV injection of Aβ1-42 (upper). Bar; 50 µm. The data (mean ± SEM) indicate the rate (%) of PI fluorescence after Aβ1-42 injection to that after saline (vehicle) injection that was indicated as 100% (lower). **, p < 0.01, vs. control/saline, ###, p < 0.001, vs. control/Aβ (Tukey’s test). control/saline, 8 slices from 3 mice; control/Aβ, 8 slices from 3 mice; NYT/Aβ, 14 slices from 5 mice