Fig. 2

Effects of CYP2A6 haplotypes and genotypes on aspirin chemoprevention for colorectal tumor recurrence in the total cohort and the nonsmoker subset of Japanese J-FAPP IV study participants. Data shown in Panel A were taken from Ishikawa et al. [15]. The preventive effects of aspirin were evaluated based on the numbers of polyps that had developed to a size of ≥5 mm (J-FAPP IV) observed after 8-months. Odds ratios are shown with respect to the reference (placebo) group