Fig. 1

Definition expressing the degree to which febrile neutropenia is blunted. The gray line shows examples of body temperature variation. TBRE: the time to body temperature reaching 37.5 °C from the time when body temperature exceeded the baseline temperature, TABE: the time to antimicrobial administration from the time when body temperature exceeded the baseline temperature, TABR: the time to antimicrobial administration from the time when body temperature reached 37.5 °C. The judgment of exceeding baseline temperature was defined as directly related to reaching 37.5 °C. TABR values can be negative